Lorena Sigaut

Lorena Sigaut
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Lorena Sigaut

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Quantitative Biology - Subcellular Processes (1)

Publications Authored By Lorena Sigaut

Many cell signaling pathways involve the diffusion of messengers that bind/unbind to intracellular components. Quantifying their net transport rate under different conditions, then requires having separate estimates of their free diffusion coefficient and binding/unbinding rates. In this paper, we show how performing sets of Fluorescence Correlation Spectroscopy (FCS) experiments under different conditions, it is possible to quantify free diffusion coefficients and on and off rates of reaction-diffusion systems. Read More