Gen Li

Gen Li
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Gen Li

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Statistics - Methodology (5)
Statistics - Machine Learning (2)
Mathematics - Rings and Algebras (1)
Statistics - Applications (1)
Mathematics - Information Theory (1)
Computer Science - Information Theory (1)

Publications Authored By Gen Li

In modern biomedical research, it is ubiquitous to have multiple data sets measured on the same set of samples from different views (i.e., multi-view data). Read More

We study a spectral initialization method that serves as a key ingredient in recent work on using efficient iterative algorithms for estimating signals in nonconvex settings. Unlike previous analysis in the literature, which is restricted to the phase retrieval setting and which provides only performance bounds, we consider arbitrary generalized linear sensing models and present a precise asymptotic characterization of the performance of the spectral method in the high-dimensional regime. Our analysis reveals a phase transition phenomenon that depends on the sampling ratio. Read More

Network topology evolves through time. A dynamic network model should account for both the temporal dependencies between graphs observed in time, as well as the structural dependencies inherent in each observed graph. We propose and investigate a family of dynamic network models, known as varying-coefficient exponential random graph models (VCERGMs), that characterize the evolution of network topology through smoothly varying parameters in an exponential family of distributions. Read More

Expression quantitative trait loci (eQTL) analysis identifies genetic markers associated with the expression of a gene. Most existing eQTL analyses and methods investigate association in a single, readily available tissue, such as blood. Joint analysis of eQTL in multiple tissues has the potential to improve, and expand the scope of, single-tissue analyses. Read More

For a matrix ${\bf A}$ with linearly independent columns, this work studies to use its normalization $\bar{\bf A}$ and ${\bf A}$ itself to approximate its orthonormalization $\bf V$. We theoretically analyze the order of the approximation errors as $\bf A$ and $\bar{\bf A}$ approach ${\bf V}$, respectively. Our conclusion is able to explain the fact that a high dimensional Gaussian matrix can well approximate the corresponding truncated Haar matrix. Read More

We describe a probabilistic PARAFAC/CANDECOMP (CP) factorization for multiway (i.e., tensor) data that incorporates auxiliary covariates, SupCP. Read More

Expression quantitative trait loci (eQTL) analyses, which identify genetic markers associated with the expression of a gene, are an important tool in the understanding of diseases in human and other populations. While most eQTL studies to date consider the connection between genetic variation and expression in a single tissue, complex, multi-tissue data sets are now being generated by the GTEx initiative. These data sets have the potential to improve the findings of single tissue analyses by borrowing strength across tissues, and the potential to elucidate the genotypic basis of differences between tissues. Read More

Motivated by the prevalence of high dimensional low sample size datasets in modern statistical applications, we propose a general nonparametric framework, Direction-Projection-Permutation (DiProPerm), for testing high dimensional hypotheses. The method is aimed at rigorous testing of whether lower dimensional visual differences are statistically significant. Theoretical analysis under the non-classical asymptotic regime of dimension going to infinity for fixed sample size reveals that certain natural variations of DiProPerm can have very different behaviors. Read More