F. Harms - LLTech SAS, Paris, France

F. Harms
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F. Harms
LLTech SAS, Paris, France

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Pub Categories

Physics - Instrumentation and Detectors (4)
Physics - Optics (3)
Physics - Medical Physics (3)
High Energy Physics - Experiment (2)
Nuclear Experiment (2)
Quantitative Biology - Tissues and Organs (1)
Physics - Biological Physics (1)
Physics - Computational Physics (1)

Publications Authored By F. Harms

The Kassiopeia particle tracking framework is an object-oriented software package using modern C++ techniques, written originally to meet the needs of the KATRIN collaboration. Kassiopeia features a new algorithmic paradigm for particle tracking simulations which targets experiments containing complex geometries and electromagnetic fields, with high priority put on calculation efficiency, customizability, extensibility, and ease of use for novice programmers. To solve Kassiopeia's target physics problem the software is capable of simulating particle trajectories governed by arbitrarily complex differential equations of motion, continuous physics processes that may in part be modeled as terms perturbing that equation of motion, stochastic processes that occur in flight such as bulk scattering and decay, and stochastic surface processes occuring at interfaces, including transmission and reflection effects. Read More

Authors: M. Arenz, M. Babutzka, M. Bahr, J. P. Barrett, S. Bauer, M. Beck, A. Beglarian, J. Behrens, T. Bergmann, U. Besserer, J. Blümer, L. I. Bodine, K. Bokeloh, J. Bonn, B. Bornschein, L. Bornschein, S. Büsch, T. H. Burritt, S. Chilingaryan, T. J. Corona, L. De Viveiros, P. J. Doe, O. Dragoun, G. Drexlin, S. Dyba, S. Ebenhöch, K. Eitel, E. Ellinger, S. Enomoto, M. Erhard, D. Eversheim, M. Fedkevych, A. Felden, S. Fischer, J. A. Formaggio, F. Fränkle, D. Furse, M. Ghilea, W. Gil, F. Glück, A. Gonzalez Urena, S. Görhardt, S. Groh, S. Grohmann, R. Grössle, R. Gumbsheimer, M. Hackenjos, V. Hannen, F. Harms, N. Hauÿmann, F. Heizmann, K. Helbing, W. Herz, S. Hickford, D. Hilk, B. Hillen, T. Höhn, B. Holzapfel, M. Hötzel, M. A. Howe, A. Huber, A. Jansen, N. Kernert, L. Kippenbrock, M. Kleesiek, M. Klein, A. Kopmann, A. Kosmider, A. Kovalík, B. Krasch, M. Kraus, H. Krause, M. Krause, L. Kuckert, B. Kuffner, L. La Cascio, O. Lebeda, B. Leiber, J. Letnev, V. M. Lobashev, A. Lokhov, E. Malcherek, M. Mark, E. L. Martin, S. Mertens, S. Mirz, B. Monreal, K. Müller, M. Neuberger, H. Neumann, S. Niemes, M. Noe, N. S. Oblath, A. Off, H. -W. Ortjohann, A. Osipowicz, E. Otten, D. S. Parno, P. Plischke, A. W. P. Poon, M. Prall, F. Priester, P. C. -O. Ranitzsch, J. Reich, O. Rest, R. G. H. Robertson, M. Röllig, S. Rosendahl, S. Rupp, M. Rysavy, K. Schlösser, M. Schlösser, K. Schönung, M. Schrank, J. Schwarz, W. Seiler, H. Seitz-Moskaliuk, J. Sentkerestiova, A. Skasyrskaya, M. Slezak, A. Spalek, M. Steidl, N. Steinbrink, M. Sturm, M. Suesser, H. H. Telle, T. Thümmler, N. Titov, I. Tkachev, N. Trost, A. Unru, K. Valerius, D. Venos, R. Vianden, S. Vöcking, B. L. Wall, N. Wandkowsky, M. Weber, C. Weinheimer, C. Weiss, S. Welte, J. Wendel, K. L. Wierman, J. F. Wilkerson, D. Winzen, J. Wolf, S. Wüstling, M. Zacher, S. Zadoroghny, M. Zboril

The KATRIN experiment will probe the neutrino mass by measuring the beta-electron energy spectrum near the endpoint of tritium beta-decay. An integral energy analysis will be performed by an electro-static spectrometer (Main Spectrometer), an ultra-high vacuum vessel with a length of 23.2 m, a volume of 1240 m^3, and a complex inner electrode system with about 120000 individual parts. Read More

We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals signals linked with local activity of the endogenous scattering elements which can reveal cells where other imaging techniques fail or need exogenous contrast agents. We benefit from the micrometric transverse resolution of full field OCT to image intracellular features. Read More

The focal-plane detector system for the KArlsruhe TRItium Neutrino (KATRIN) experiment consists of a multi-pixel silicon p-i-n-diode array, custom readout electronics, two superconducting solenoid magnets, an ultra high-vacuum system, a high-vacuum system, calibration and monitoring devices, a scintillating veto, and a custom data-acquisition system. It is designed to detect the low-energy electrons selected by the KATRIN main spectrometer. We describe the system and summarize its performance after its final installation. Read More

Semiconductor detectors in general have a dead layer at their surfaces that is either a result of natural or induced passivation, or is formed during the process of making a contact. Charged particles passing through this region produce ionization that is incompletely collected and recorded, which leads to departures from the ideal in both energy deposition and resolution. The silicon \textit{p-i-n} diode used in the KATRIN neutrino-mass experiment has such a dead layer. Read More

A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of Full-Field Optical Coherence Tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1\mum resolution in 3D with a typical 200\mum imaging depth. A 1cm2 specimen is scanned at a single depth and processed in about 5 minutes. Read More

Affiliations: 1Institut Langevin ESPCI ParisTech, Paris, France, 2Department of Pathology, Tenon Hospital APHP, Paris, France, 3Department of Tumor Biology, Institut Curie, Paris, France, 4Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Tx, USA, 5LLTech SAS, Paris, France, 6Institut Langevin ESPCI ParisTech, Paris, France, 7LLTech SAS, Paris, France, 8Institut Langevin ESPCI ParisTech, Paris, France

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) is used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative diagnoses. Our aim included evaluating the safety of FF-OCT on human tissue and determining the concordance between the images obtained with routinely prepared histopathological material. The compact device used for this study provides a 2 {\mu}m-lateral and a 1 {\mu}m-axial resolution, and is able to scan a 1. Read More